Bjorn Steffensen, DDS, MS, Ph.D.
Professor
Departments of Periodontics and Biochemistry
D.D.S., The Royal Dental College of Copenhagen, 1978,
M.S.,  University of Michigan, 1986
Ph.D., University of British Columbia, 1997

Telephone:    (210) 567-3564
Fax:              (210) 567-6858
E-mail:          SteffensenB@uthscsa.edu

Research focus of the laboratory

The laboratory investigates the biology of the extracellular matrix associated with health and disease. The central focus areas are the interactions between extracellular matrix components, the roles of these molecules in modifying cell behavior, and the contributions of their structural domains and modules to their overall functions. Our working hypothesis is that cells contacting structurally altered matrix molecules modify their behavior. Whereas such modifications may contribute in a positive way to normal homeostasis, they could also form the basis for negative events such as delayed wound healing and contribute to cancer cell invasion. Molecules of special interest are matrix metalloproteinases (MMPS), collagens, and fibronectin. Within this framework, we are addressing a number of research questions.

Location and facilities
 
Our laboratory is located in the Department of Periodontics at the University of Texas Health Science Center at San Antonio (UTHSCSA). The building is physically structured such that we are directly connected to the other departments and schools of the institution, including the Schools of Medicine and Graduate School of Biomedical Sciences (Biochemistry, Physiology, Cell and Structural Biology). This facilitates and provides ample opportunities for collaborations. Our laboratory is well equipped for cell and molecular biology as well as biochemical research projects. Additional access to specialized equipment and core facilities is available as needed at the Heath Science Center. With good funding from the NIH and other agencies, we are currently in a strong position to pursue our research goals.

Opportunities

We welcome inquiries from individuals interested in pursuing graduate studies, postdoctoral positions, or visiting faculty with a sincere interest in our line of research. The University of Texas Health Science Center is an equal opportunity employer.